This study, published by Matlashewski et al. in PLoS NTDs, evaluates the sensitivity of the rK39 diagnostic test with whole blood. The rK39 is used to diagnosse Visceral Leishmaniasis (VL) with serum, not whole blood. Samples were collected from patients attending an outpatient clinical in Patna India and serum and whole blood test results compared. It was concluded that the concordance was excellent but it is possible to miss rK39 positive individuals when using blood and the titer of anti-rK39 antibodies is low.
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