A Point-of-Care Assay to Detect Antimalarial Drugs from Finger Stick Blood Samples
by The Editorial TeamThis video seminar describes research to develop a low-cost, field-based test to detect several slow-clearing ACT drug compounds from unprocessed fingerstick blood samples
The European Mobile Laboratory, EMLab, was the first EBOV diagnostics unit deployed to the outbreak epicentre by WHO in March 2014.
Laboratory systems and diagnostic technologies are a critical pillar in the fight against malaria. The World Health Organization (WHO) recommends diagnostic testing for all people with suspected malaria before treatment is administered.
Call for Papers: Special issue on strengthening tuberculosis diagnostic networks in Africa - African Journal of Laboratory Medicine
From our colleagues at the African Society for Laboratory Medicine (ASLM) - The Role of Public Health Institutes in Achieving Public Health Goals
East African Leaders Join Together to Develop Country-Specific Plans for Point-of-Care Testing.
Pioneering New Diagnostics: Addressing Challenges and Implications for Point-of-Care Testing in African Settings
by Laurel OldachA Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections
by Kfir Oved, et alHIV/AIDS diagnostics technology landscape
by UnitaidNeglected Diseases, Delinquent Diagnostics
by Mark KesselAn article highlighting the importance of diagnostics for NTDs, and providing a good overview on their development from a policy perspective.
Prioritizing Congenital Syphilis Control in South China: A Decision Analytic Model to Inform Policy Implementation
by Nicholas X. Tan, Chara Rydzak, Li-Gang Yang, Peter Vickerman, Bin Yang, Rosanna W. Peeling, Sarah Hawkes, Xiang-Sheng Chen, Joseph D. TuckerPostmarket Surveillance of Medical Devices: A Comparison of Strategies in the US, EU, Japan, and China
by Daniel B. Kramer, Yongtian T. Tan, Chiaki Sato, Aaron S. KesselheimValidation of Two Rapid Diagnostic Tests for Visceral Leishmaniasis in Kenya
by Jane Mbui, Monique Wasunna, Manica Balasegaram, Adrian Laussemayer, Rashid Juma, Simon Njoroge Njenga, George Kirigi, Mark Riongoita, Roberto de la Tour, Joke van Peteghem, Raymond Omollo, Francois ChappuiUse of Expert Panels to Define the Reference Standard in Diagnostic Research: A Systematic Review of Published Methods and Reporting
by Loes c. M. Vertens, Berna D. L. Broekhuizen, Christiana A. Naaktgeboren, Frans H. Rutten, Amy W. Hoes, Yvonne van Mourik, Karel G. M. Moons, Johannes B. ReitsmaHow to Improve the early Diagnosis of Trypanosoma cruzi Infection: Relationship between Validated Conventional Diagnosis and Quantitative DNA Amplification in Congenitally Infected Children
by Jacqueline Bua, Bibiana J. Volta, Alina E. Perrone, Karenina Scollo, Elsa B. Velazquez, Andres M. Ruiz, Ana M. De Rissio, Rita L. CardoniIdentification of Seroreactive Proteins of Leptospira interrogans Serovar Copenhageni Using a High-Density Protein Microarray Approach
by Carolina Lessa-Aquino, Camila Borges Rodrigues, Jozelyn Pablo, Rie Sasaki, Algis Jasinskas, Li Liang, Elsio A. Wunder Jr, Guilherme S. Ribeiro, Adam Vigil, Ricardo Galler, Douglas Molina, Xiaowu Liang, Mitermayer G. Reis, Albert I. Ko, Marco Alberto Medeiros, Philip L. FelgnerDiagnostic Accuracy of Loopamp Trypanosoma brucei Detection Kit for Diagnosis of Human African Trypanosomiasis in Clinical Samples
by Patrick Mitashi, Epco Hasker, Dieudonne Mumba Ngoyi, Pati Patient Pyana, Veerle Lejon, Wim Van der Veken, Pascal Lutumba, Philippe Buscher, Marleen Boelaert, Stijn Deborggraeve
Analytical and Clinical Performance of the CDC Real Time RT-PCR Assay for Detection and Typing of Dengue Virus
by Gilberto A Santiago, Edgardo Vergne, Yashira Quiles, Joan Cosme, Jesus Vazquez, Juan F. Medina, Freddy Medina, Candimar Colon, Harold Margolis, Jorge L. Munoz-JordanEvaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood in Lymphocytes in Patients in Dhaka, Bangladesh
by Farhana Khanam, Alaullah Sheikh, Abu Sayeed, Saraur Bhuiyan, Feroza Kaneez Choudhury, Umme Salma, Shahnaz Pervin, Tania Sultana, Dilruba Ahmed, Doli Goswami, Lokman Hossain, KZ Mamun, Richell C Charles, W. Abdullah Brooks, Stephen B. Calderwood, Alejandro Cravioto, Edward T Ryan, Firdausi QadriProspective Evaluation of Three Rapid Diagnostic Tests for Diagnosis of Human Leptospirosis
by Marga GA Goris, Mariska MG Leeflang, Martin Loden, Jiri FP Wagenaar, Paul Klatser, Rudy A Hartseerl, Kimberly R BoerRandomised Clinical Trial Investigating the Specificity of Novel Skin Test (C-Tb) for Diagnosis of M. tuberculosis Infection
by Henrik Aggerbeck, Rafaela Giemza, Paulatsya Joshi, Pernille N. Tingskov, Soren T. Hoff, Julia Boyle, Peter Andersen, David J. M. LewisDiagnosis of Visceral Leishmaniasis in Bihar India: Comparison of the rK39 Rapid Diagnostic Test on Whole Blood Versus Serum
by Greg Matlashewski, Vidya Nand Ravi Das, Krishna Pandey, Dharmendra Singh, Sushmita Das, Ayan Kumar Ghosh, Ravindra Nath Pandey, Pradeep DasXpert MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults
by Karen R Steingart, Hojoon Sohn, Ian Schiller, Lorie A Kloda, Catharine C Boehme, Madhu Pai, Nandini DendukuriRapid Syphilis Testing Uptake for Female Sex Workers at Sex Venues in Southern China: Implication for Expanding Syphilis Screening
by Xiang-Sheng Chen, Yeu-Ping Yin, Crystal Shen, Guo-Gu Liu, Zheng-Jun Zhu, Wan-Hui Wei, Hong-Chun Wang, Shui-Jie Huang, Jing Li, Joseph D Tucker, David Mabey, Rosanna PeelingDevelopment and Validation of a Novel Diagnostic Test for Human Brucellosis Using a Glyco-engineered Antigen Coupled to Magnetic Beads
by Andrés E. Ciocchini, Diego A. Rey Serantes, Luciano J. Melli, Jeremy A. Iwashkiw, Bettina Deodata, Jorge Wallach, Mario F. FEldman, Juan E. Ugalde, Diego J. ComerciDiagnosis of Brugian Filariasis by Loop- Mediated Isothermal Amplification
by Catherine B. Poole, Nathan A. Tanner, Yinhua Zhang, Thomas C. Evans Jr., Clotilde K. S. CarlowLeishmaniasis Direct Agglutination Test: Using Pictorials as Training Materials to REduce Inter-Reader Variability and Improve Accuracy
by Emily R Adams, Diane Jacquet, Gerard Schoone, Kamlesh Gidwani, Marleern Boelaert, Jane CunninghamField Evaluation and Impact on Clinical Management of a Rapid Diagnostic Kit That Detects Dengue NS1, IgM and IgG
by Anne-Claire Andries, Veasna Duong, Chantha Ngan, Sivuth Ong, Rekol Huy, Kim Kim Sroin, Vantha Te, Bunthin Y, Patrich Lorn Try, Philippe BuchyUptake of Home-Based Voluntary HIV Testing in Sub-Saharan Africa: A Systematic Review and Met-Analysis
by Kalpana Sabapathy, Rafael Van den Bergh, Sarah Fidler, Richard Hayes, Nathan FordPopulation Health Impact and Cost-effectiveness of Tuberculosis Diagnosis with Xpert MTB/RIF
by NA Menzies, T Cohen, H-H Lin, M Murray, JA SalomonPoint of Care Testing for Infectious Diseases: Diversity, Complexity and Barriers in Low- and Middle Income Countries
by Nitika Pant Pai, MD MPH PhD, Caroline Vadnais, Claudia Denkinger, Nora Engel, Madhu PaiThe Future of Diagnostic Microbiology – whole genome sequencing?
by Susanna DunachieVisceral leishmaniasis: what are the needs for diagnosis, treatment and control?
by François Chappuis, Shyam Sundar, Asrat Hailu, Hashim Ghalib, Suman Rijal, Rosanna W. PeelingDiagnosis of visceral leishmaniasis
by Pankaj Srivastava, Anand Dayama, Sanjana Mehrotra, Shyam SundarEnteric fever diagnostics reviews
by Paula Bianca BlomquistMicrofluid technologies
by Paula Bianca BlomquistMobile Phone Based Clinical Microscopy for Global Health Applications
by David N. Breslauer, Robi N. Maamari, Neil A. Switz, Wilbur A. Lam, Daniel A. FletcherCould u txt me ur blood sample?
by Colin BarrasWeb-Based Virtual Microscopy for Parasitology: A Novel Tool for Education and Quality Assurance
by Ewert Linder, Mikael Lundin, Cecilia Thors, Marianne Lebbad, Jadwiga Winiecka-Krusnell, Heikki Helin, Byron Leiva, Jorma Isola, Johan LundinDirect susceptibility testing for multi drug resistant tuberculosis: a meta-analysis
by Freddie Bwanga, Sven Hoffner, Melles Haile, Moses L JolobaAlternative methods of diagnosing drug resistance - What can they do for me?
by David AJ Moore, N Sarita ShahFirst International External Quality Assessment of Molecular Detection of Crimean-Congo Hemorrhagic Fever Virus
by Camille Escadafal, Stephan Olschlager, Tatjana Avsic Zupanc, Anna Papa, Jessica Vanhomwegen, Roman Wolfel, Ali Mirazimi, Annette Teichmann, Oliver Donoso Mantke, Matthias NiedriqThe Human African Trypanosomiasis Specimen Biobank: A Necessary Tool to Support Research of New Diagnostics
by Jose R Franco, Pere P Simarro, Abdoulaye Diarra, Jose A. Ruiz-Postigo, Jean G. JanninPoint-of-Care Tests to Strengthen Health Systems and Save Newborn Lives: The Case of Syphilis
by David Mabey, Kimberly Sollis, Helen Kelly, Adele Schwartz Benzaken, Edward Bitarakwate, John Changalucha, Xiang-Sheng Chen, Yue-Pin Ying, Patricia Garcia, Susan Strasser, Namwinga Chintu, Tikki Pang, Fern Terris-Prestholt, Sedona Sweeney, Rosanna PeelingA Research Agenda for Helminth Diseases of Humans: Diagnostics for Control and Elimination Programmes
by James S. McCarthy, Sara Lustigman, Guo-Jing Yang, Rashida M. Barakat, Héctor H. García, Banchob Sripa, Arve Lee Willingham, Roger K. Prichard, María-Gloria BasáñezDiagnostic Accuracy of Molecular Amplification Tests for Human African Trypanosomiasis—Systematic Review
by Claire M. Mugasa, Emily R. Adams, Kimberly R. Boer, Heleen C. Dyserinck, Philippe BüscherTowards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis
by Enock Matovu, Anne Juliet Kazibwe, Claire Mack Mugasa, Joseph Mathu Ndungu, Zablon KithingiFree treatment, rapid malaria diagnostic tests and malaria village workers can hasten progress toward achieving the malaria related millennium development goals
by Katie Tayler-Smith, Alice Kociejowski ,1,3 ,3 Mit, Nadine de Lamotte, Seco Gerard, Frederique Ponsar, Mit Philips, Rony ZachariahToward fast malaria detection by secondary speckle sensing microscopy
by Dan Cojoc, Sara Finaurini, Pavel Livshits, Eran Gur, Alon Shapira, Vicente Mico, Zeev ZalevskyNucleic acid amplification testing for Neisseria gonorrhoeae: an ongoing challenge
by David M Whiley, John W Tapsall, Theo P SlootsEarly infant diagnosis of HIV infection in Zambia through mobile phone texting of blood test results
by Phil Seidenberg, Stephen Nicholson, Merrick Schaefer, Katherine Semrau, Maximillian Bweupe, Noel Masese, Rachael Bonawitz, Lastone Chitembo, Caitlin Goggin, Donald M TheaOptimal monitoring strategies for guiding when to switch first-line antiretroviral therapy regimens for treatment failure in adults and adolescents
by LW Chang, J Harris, E HumphreysMonitoring HIV Antiretroviral Therapy in Resource-Limited Settings: Time to Avoid Costly Outcomes
by Motasim Badri, Stephen D Lawn, Robin WoodMulti-site evaluation of a point-of-care instrument for CD4+ T cell enumeration using venous and finger prick blood: the PIMA CD4
by Papa Alassana Diaw, Geraldine Daneau, Abdoul Coly, Birahim Pierre Ndiaye, Dribril Wade, Makhtar Camara, Souleymane Mboup, Luc Kestens, Tandakha Ndiaye DieyeProviding Immediate CD4 Count Results at HIV Testing Improves ART Initiation
by Mamsallah Faal, Nicolette Naidoo, Deborah K. Glencross, Willem D. F. Venter, Regina OsihCD4+ cell count testing more effective than HIV disease clinical staging in identifying pregnant and postpartum women eligible for antiretroviral therapy in resource-limited settings
by Rosalind Carter, Kate Dugan, Wafaa El-Sadr, Landon Myer, Juliana Otieno, Nattaya Pungpapong, Patricia Toro, Elaine AbramsWhy do we need a point-of-care CD4 test for low-income countries?
by R. Zachariah, S. Reid, P. Chaillet, M. Massaquoi, E. Schouten, A. HarriesThis review, written by Ruth McNerney and Peter Daley, provides an overview of the state of research into point-of-care diagnostics for active tuberculosis and highlights the barriers to the development of these tests.